THE ORAL BIOAVAILABILITY, EXCRETION AND CYTOCHROME P450 INHIBITION PROPERTIES OF EPIBERBERINE: AN IN VIVO AND IN VITRO EVALUATION

The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

Ning Chen,1 Xiao-yan Yang,1,2 Chang-e Guo,1 Xin-ning Bi,1 aluminum lotion Jian-hua Chen,1 Hong-ying Chen,1 Hong-pin Li,1 Hong-ying Lin,1 Yu-jie Zhang1 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 2Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, China Abstract: Epiberberine (EPI) is a novel and potentially e

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Advances in nanotechnology for the treatment of GBM

Glioblastoma (GBM), a highly malignant glioma of the central nervous system, is the most dread and common brain tumor with a high rate of therapeutic resistance and recurrence.Currently, the clinical treatment methods are surgery, radiotherapy, read more and chemotherapy.However, owning to the highly invasive nature of GBM, it is difficult to compl

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